Kodi magazi atsopano a Biomer angathandize kuneneratu za chiopsezo cha Alzheimer?

Kafukufuku watsopano akusonyeza kuti astrocytes, mtundu wa khungu la ubongo, ndikofunikira kuti mulumikiza amyloiid-β ndi magawo oyamba a matenda a Tau. Karyna Bartashevich / Stocksy

• Zogwira Alendo, Mtundu wa khungu la ubongo, lingathandize asayansi kumvetsetsa chifukwa chake anthu ena omwe ali ndi vuto la thanzi ndi a amyloiid-Β sakupanga zizindikiro zina za Alzheimer's, monga mapuloteni owoneka bwino a Tau.
• Kafukufuku woposa 1,000 adayang'ana kwa malo opezeka biomaker ndipo amapeza kuti amyloiid-β adangolumikizidwa ndi kuchuluka kwa tau kwa anthu omwe ali ndi zizindikiro za Astromyte.
• Zomwe zimapezeka zikusonyeza kuti Astrowcytes ndiofunikira kuti alumikiza amyloiid-Β ndi magawo oyamba a matenda a Tau, zomwe zitha kusintha momwe timatanthauzira matenda oyambirira a Alzheimer's.

Kuchuluka kwa malo amtundu wa Amyloiird ndi mapuloteni owoneka bwino mu ubongo nthawi yayitali amadziwika kuti choyambitsaMatenda a Alzheimer's (AD).

Kukula kwa mankhwala kwathandiza kuyang'ana kwambiri amyloiid ndi Tau, kunyalanyaza udindo wa njira za ubongo wina, monga ma neuroimmune dongosolo.

Tsopano, kafukufuku watsopano kuchokera ku yunivesite ya Pittsburgh Sukulu ya zamankhwala akuwonetsa kuti ziwopsezo za ubongo, zomwe zimagwira ntchito yofunika kwambiri pofotokoza zakuda za Alzheimer's.

Kudalira Kwambiriochuluka mu minofu yaubongo. Pamodzi ndi maselo ena a ubongo, ma cell a ubongo wa ubongo, matsenga amathandizira ma neurons powapatsa michere, mpweya, ndi kutetezedwa ku tizilombo toyambitsa matenda.

M'mbuyomu udindo wa Astrocyte mu kulumikizana kwa neuronal udasokonekera chifukwa maselo onyezimira samachita magetsi ngati ma neuron. Koma yunivesite ya Pittsburg imatsutsa lingaliro ili ndikuwunika pa udindo wovuta wa Astrocyte muubongo ndi matenda.

Zopezazo zidasindikizidwa posachedwaChilengedwe Chakudya Chodziwikiratu.

Kafukufuku wapitawu akusonyeza kuti kusokonekera m'machitidwe a ubongo kupitirira zolemetsa, monga kutupa kwa ubongo, kungagwire ntchito yotupa muimfa ya kufa kwa neuronial.

Mu phunziroli watsopanowu, ofufuza adayesanso magazi pa omwe ali ndi maphunziro atatu osiyana omwe amakhudzana ndi achikulire achikulire omwe ali ndi vuto lokhala ndi ma amyloid.

Amasanthula zitsanzo za magazi kuti ayesetse kusokonekera kwa Astrocyte Fibrillary acid protein (GFAP), kuphatikiza ndi kukhalapo kwa matenda a Titelogical Tau.

Ofufuzawo adazindikira kuti okhawo omwe anali ndi zikwangwani zam'madzi komanso zolembera magazi zomwe zimawonetsa kuyambitsa kwa Asnormyte kapena kukhala ndi mwayi wokhala ndi chizindikiro cha Alzheimer mtsogolo.